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Faculty

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  • Department of Pharmacy

Dr. Achal Mishra
Professor and Head
About

Educational Qualication M.Pharm, Ph.D
Area of Interest Drug Designing, Organic Synthesis
Research Projects

  • “QSAR analysis of some derivatives of quinoxaline as antimalarial agent” compleatedChhattisgarh Council of Science & Technology (CGCOST), Rs 4,00000.00 Completed in 2018.
Patent Published
  • AI Based Safe Healthcare System For Fertility Preservation for Young Women with Breast Cancer Using Cloud and Machine Learning Algorithms, Application No. 202211020763 A, Publication Date: 22/04/2022.
Book Chapter
  • Isatine derivative as human carboxylestarase inhibitors : an approach towards 3D-QSAR, pharmacophore and moleculear docking , B.P. International Publication. Current Aspects in Pharmaceutical Research and Development Vol. 2, 18 September 2021 , Page1-21, https://doi.org/10.9734/bpi/caprd/v2/12980D
  • A Molecular Docking Study bring Golden Era in Pharmaceutical Drug Design and Chemical Engineering Process, Bharti Publication, India. ISBN NO.-978-93-91681-17-3
Journals Publications
  • Mishra A, Jha V, Rajak H. Molecular structural investigations of quinoxaline derivatives through 3D-QSAR, molecular docking, ADME prediction and pharmacophore modeling studies for the search of novel antimalarial agent. Journal of the Indian Chemical Society. 2022 Jan 5:100343. ISSN 0019-4522. https://doi.org/10.1016/j.jics.2022.100343.
  • Agrawal M, Dwivedi J, Kishore D, Jain S, Mishra A, Jain S, Sharma S. An Expeditious Approach to the Synthesis of Novel Quinolino and Diazacino Condensed Analogues of Azepino [3, 2-b] Carbazole-2-one of Medicinal Interest. Indian Journal of Pharmaceutical Education and Research. 2022 Jan 1;56(1):S89-97. ISSN 0019-5464. Doi : 10.5530/ijper.56.1s.47.
  • Mishra A, Vaishnav Y, Jha AK, Verma S. 3D QSAR analysis on quinoxaline derivatives as anti-malarial using K-nearest neighbour molecular field analysis. Indian Journal of Chemistry-Section B (IJC-B). 2021 Jun 29;60(5):727-31. ISSN 0975-0983.
  • Mishra A, Waghela R. A Comparative Study of Approved Drugs for SARS-CoV-2 by Molecular Docking. Journal of Molecular Docking. 2021 Jun 30;1(1):25-31. ISSN 2798-138X. https://doi.org/10.33084/jmd.v1i1.2148.
  • Dewangan D, Vaishnav Y, Mishra A, Jha AK, Verma S, Badwaik H. Synthesis, molecular docking, and biological evaluation of Schiff base hybrids of 1, 2, 4-triazole-pyridine as dihydrofolate reductase inhibitors. Current Research in Pharmacology and Drug Discovery. 2021 Jan 1;2:100024. ISSN 2590-2571. https://doi.org/10.1016/j.crphar.2021.100024
  • Arya R, Paliwal S, Gupta SP, Sharma S, Madan K, Mishra A, Verma K, Chauhan N. In-silico Studies and Biological Activity of Potential BACE-1 Inhibitors. Combinatorial Chemistry & High Throughput Screening. 2021 Jun 1;24(5):729-36. ISSN 1875-5402 1386-2073.0.2174/1386207323999200918151331.
  • Vaishnav Y, Dewangan D, Verma S, Mishra A, Thakur AS, Kashyap P, Verma SK. PPAR gamma targeted molecular docking and synthesis of some new amide and urea substituted 1, 3, 4‐thiadiazole derivative as antidiabetic compound. Journal of Heterocyclic Chemistry. 2020 May;57(5):2213-24. ISSN 1943-5193.https://doi.org/10.1002/jhet.3941.
  • Dewangan D, Nakhate K, Mishra A, Thakur AS, Rajak H, Dwivedi J, Sharma S, Paliwal S. Design, Synthesis, and Characterization of Quinoxaline Derivatives as a Potent Antimicrobial Agent. Journal of Heterocyclic Chemistry. 2019 Feb;56(2):566-78. ISSN 1943-5193. https://doi.org/10.1002/jhet.3431.
  • Arya R, Gupta SP, Paliwal S, Kesar S, Mishra A, Prabhakar YS. QSAR and molecular modeling studies on a series of pyrrolidine analogs acting as BACE-1 Inhibitors. Letters in Drug Design & Discovery. 2019 Jul 1;16(7):746-60. ISSN 1875-628X 1570-1808. 10.2174/1570180815666180627124422.
  • Dhall E, Jain S, Mishra A, Dwivedi J, Sharma S. Synthesis and Evaluation of Some Phenyl Substituted Azetidine Containing 1, 2, 4‐triazole Derivatives as Antibacterial Agents. Journal of Heterocyclic Chemistry. 2018 Dec;55(12):2859-69. ISSN 1943-5193. https://doi.org/10.1002/jhet.3357.
  • Dewangan D, Nakhate KT, Verma VS, Nagori K, Badwaik H, Nair N, Tripathi DK, Mishra A. Synthesis and Molecular Docking Study of Novel Hybrids of 1, 3, 4‐Oxadiazoles and Quinoxaline as a Potential Analgesic and Anti‐Inflammatory Agents. Journal of Heterocyclic Chemistry. 2018 Dec;55(12):2901-10. ISSN 1943-5193. https://doi.org/10.1002/jhet.3363
  • Misra A, Sharma S, Sharma D, Dubey S, Mishra A, Kishore D, Dwivedi J. Synthesis and molecular docking of pyrimidine incorporated novel analogue of 1, 5-benzodiazepine as antibacterial agent. Journal of Chemical Sciences. 2018 Mar;130(3):1-2. ISSN 0974-3626. https://doi.org/10.1007/s12039-018-1430-7.
  • Vaishnav Y, Thakur A, Kaur CD, Verma S, Mishra A, Jain SK, Ghode P. QSAR Analysis of some N, N-diphenyl urea derivatives as CCR5 Receptor Antagonist. Research Journal of Pharmacy and Technology. 2018;11(9):3802-10. ISSN 0974-360X 0974-3618. DOI: 10.5958/0974-360X.2018.00697.2
  • Paliwal S, Sharma S, Dwivedi J, Mishra A. Synthesis of Novel Substituted Phenyl‐3‐Hydrazinyl‐Quinoxaline‐2‐Amine Derivatives: Evaluation of Antimicrobial Activity and Its Molecular Docking Studies. Journal of Heterocyclic Chemistry. 2017 Nov;54(6):3689-95. ISSN 1943-5193. https://doi.org/10.1002/jhet.3003.
  • Mishra A, Paliwal S, Sharma S, Dwivedi J. Synthesis and Molecular Docking Studies of Some New Quinoxaline Derivatives as Potential Antimicrobial Agents. Indian Journal of Heterocyclic Chemistry. 2017 Jul 1;27(3):249-54. ISSN 0971-1627 2456-4311.
  • Sanmati KJ, Achal M. 3D QSAR Analysis on Isatin Derivatives as Carboxyl Esterase Inhibitors Using K-Nearest Neighbor Molecular Field Analysis. J Theor Comput Sci. 2015 May;2(2):1-2. ISSN 0019-5464. DOI:10.4172/2376-130X.1000124.
  • Achal Mishra, Bhavna Yadav, Shekhar Verma, Yashwant Swarnakar, A.K. Jha, Permanand Verma, Devendra Sahu. A Short Review on Concept and Types of Combinatorial Chemistry, Asian Journal of Research in Chemistry, 7, 2, 2014, 243-248. 0974-4150(Online), 0974-4169(Print). ISSN 0019-5464.
  • Achal Mishra, Takesh Kumar Nagwanshi, Reman lal Sahu, Lokendra Kumar Verma, Ruchi Yadav. A review on quinoxaline - pharmacophore and derivatives with diverse biological properties, world journal of pharmacy and pharmaceutical sciences, 2,6, 2013, 6486-6506. ISSN- 2278-4357. ISSN 0019-5464.
  • Naveen K. Mahobia, Sanmati K. Jain, Roshan Patel, Sudarshan K. Singh , Achal Mishra, Ravindra Dhardubey. 3D QSAR Analysis of Some Piperidinyl Amide and Ureas as CCR5 Antagonist, Journal of Pharmacy Research 5, 9, 2012, 4706-4709. ISSN: 0974-6943,
  • Achal Mishra, Harish Rajak, Green Chemistry: an insight into recent advances and their application in academics and research, India journal of education (CSIR), 35, 2012, 22-28. ISSN- 0971-3034.
  • Dhansay Dewangan, Achal Mishra, Alok Pandey, Shekhar Verma, Ravindra Dhar Dubey. Synthesis of Schiff bases of 2-amino-5-aryl-1, 3, 4-thiadiazole And Its Analgesic, Anti-Inflammatory, Anti-Bacterial and Anti-Tubercular Activity”, International Journal of ChemTech Research, 3, 1, 2011, 178-184. ISSN (online) 2455-9555, (print) 0974-4290.
  • S. S. Pancholi, Rajkumar Agrawal, Achal Mishra. QSAR on Heteroaryl-Phenyl-Substituted Pyrazole Derivatives as Selective and Potent Canine COX-2 Inhibitors, Current Pharmaceutical Science, 02, 2011, 68-76. ISSN-2250-2688.
  • Sanmati K. Jain, Ravindra D. Dubey, S. Mallick, S. Nag, A. Yadav, Achal Mishra Naveen K. Mahobia. 2D and 3D-QSAR Analysis of some 1, 3-disubstituted Urea Derivativesfor Anti proliferative Activity. Der Pharma Chemica, 2, 6, 2010, 125-133. ISSN 0975-413x.
  • Naveen K. Mahobia, Roshan D. Patel, Naheed W. Sheikh, Sudarshan K. Singh , Achal Mishra, Ravindra Dhardubey. Validation Method Used In Quantitative Structure Activity Relationship, Der Pharma Chemica, 2, 5, 2010, 260-271. ISSN 0975-413x.
  • Parmanand Verma, Alpna Ram, Arvind Kumar Jha, Achal Mishra, Alok Thakur. Phosphatidylcholine: a revolution in drug delivery technology, international journal of pharmaceutical sciences and research, 2010, 1, 2. 2010 ISSN (Online): 0975-8232, ISSN (Print): 2320-5148.
Awards/Recognitions
  1. Invited speaker at national or conference/seminar, Use of free available tools to improve docking pose, organized by Columbia institute of pharmacy, sponsored by AICTE, Dated 05-10 April-2021.
  2. Invited speaker at national or conference/seminar, Molecular Docking using Arguslab organized by Columbia institute of pharmacy, sponsored by AICTE, 17-22 Mayl-2021.
  3. Invited speaker at national or conference/seminar Molecular Docking using free available software live demo organized by Raja Rambapu College of Pharmacy, Kesegaon, Maharastra, Dated 13th April 2020.
  4. As Reviewer for journal Applied Organomatali Chemistry, Wiley publication.
  5. As Reviewer for journal of heterocyclic Chemistry, Wiley publication.
Conferences/Workshops/STTPs Organized
  • Organizing Secretary, “Rajiv Gandhi National Institute of Intellectual property management Government of India sponsored One day on “Intellectual property Rights (IPR), Patents and Design Filing”, 23rd February 2021.
Training Programmes/Workshops Attended
  • Two week refresher programme (Online mode) on Refresher course in Pharmacy Modern tools used in drug discovery and pharmaceutical technology, conducted by UGC- Pt. Ravishankar Shukla University Raipur on 6 Dec.-20 Dec.-2021.
  • Three days short term course on intellectual property rights, conducted by UGC- Pt. Ravishankar Shukla University Raipur on 27 Jan. 2022- 29 Jan. 2022.
  • One month Innovation Ambassador training (Foundation Level) programme conducted by MoE's Innovation Cell & AICTE on 30June-30July-2021.
  • FDP-international workshop on tools and techniques to perform molecular modelling and computer-aided drug design conducted by NIPER, Gov. of India on 11-17 Jan.2021.
Membership to Professional Bodies
  • Life Member, Indian Pharmaceutical Association (IPA).
  • Member of Indian Chemical Society (ICS).
  • Member Pharmacy Council of India (PCI).